1,157 research outputs found
The stransverse mass, MT2, in special cases
This document describes some special cases in which the stransverse mass,
MT2, may be calculated by non-iterative algorithms. The most notable special
case is that in which the visible particles and the hypothesised invisible
particles are massless -- a situation relevant to its current usage in the
Large Hadron Collider as a discovery variable, and a situation for which no
analytic answer was previously known. We also derive an expression for MT2 in
another set of new (though arguably less interesting) special cases in which
the missing transverse momentum must point parallel or anti parallel to the
visible momentum sum. In addition, we find new derivations for already known
MT2 solutions in a manner that maintains manifest contralinear boost invariance
throughout, providing new insights into old results. Along the way, we stumble
across some unexpected results and make conjectures relating to geometric forms
of M_eff and H_T and their relationship to MT2.Comment: 11 pages, no figures. v2 corrects minor typos. v3 corrects an
incorrect statement in footnote 8 and inserts a missing term in eq (3.9). v4
and v5 correct minor typos spotted by reader
Sqrt{shat}_{min} resurrected
We discuss the use of the variable sqrt{shat}_{min}, which has been proposed
in order to measure the hard scale of a multi parton final state event using
inclusive quantities only, on a SUSY data sample for a 14 TeV LHC. In its
original version, where this variable was proposed on calorimeter level, the
direct correlation to the hard scattering scale does not survive when effects
from soft physics are taken into account. We here show that when using
reconstructed objects instead of calorimeter energy and momenta as input, we
manage to actually recover this correlation for the parameter point considered
here. We furthermore discuss the effect of including W + jets and t tbar+jets
background in our analysis and the use of sqrt{shat}_{min} for the suppression
of SM induced background in new physics searches.Comment: 23 pages, 9 figures; v2: 1 figure, several subsections and references
as well as new author affiliation added. Corresponds to published versio
Supersymmetric particle mass measurement with the boost-corrected contransverse mass
A modification to the contransverse mass (MCT) technique for measuring the
masses of pair-produced semi-invisibly decaying heavy particles is proposed in
which MCT is corrected for non-zero boosts of the centre-of-momentum (CoM)
frame of the heavy states in the laboratory transverse plane. Lack of knowledge
of the mass of the CoM frame prevents exact correction for this boost, however
it is shown that a conservative correction can nevertheless be derived which
always generates an MCT value which is less than or equal to the true value of
MCT in the CoM frame. The new technique is demonstrated with case studies of
mass measurement with fully leptonic ttbar events and with SUSY events
possessing a similar final state.Comment: 33 pages, 33 .eps figures, JHEP3 styl
Reducing combinatorial uncertainties: A new technique based on MT2 variables
We propose a new method to resolve combinatorial ambiguities in hadron
collider events involving two invisible particles in the final state. This
method is based on the kinematic variable MT2 and on the MT2-assisted-on-shell
reconstruction of invisible momenta, that are reformulated as `test' variables
Ti of the correct combination against the incorrect ones. We show how the
efficiency of the single Ti in providing the correct answer can be
systematically improved by combining the different Ti and/or by introducing
cuts on suitable, combination-insensitive kinematic variables. We illustrate
our whole approach in the specific example of top anti-top production, followed
by a leptonic decay of the W on both sides. However, by construction, our
method is also directly applicable to many topologies of interest for new
physics, in particular events producing a pair of undetected particles, that
are potential dark-matter candidates. We finally emphasize that our method is
apt to several generalizations, that we outline in the last sections of the
paper.Comment: 1+23 pages, 8 figures. Main changes in v3: (1) discussion at the end
of sec. 2 improved; (2) added sec. 4.2 about the method's dependence on mass
information. Matches journal versio
The impact of the ATLAS zero-lepton, jets and missing momentum search on a CMSSM fit
Recent ATLAS data significantly extend the exclusion limits for
supersymmetric particles. We examine the impact of such data on global fits of
the constrained minimal supersymmetric standard model (CMSSM) to indirect and
cosmological data. We calculate the likelihood map of the ATLAS search, taking
into account systematic errors on the signal and on the background. We validate
our calculation against the ATLAS determinaton of 95% confidence level
exclusion contours. A previous CMSSM global fit is then re-weighted by the
likelihood map, which takes a bite at the high probability density region of
the global fit, pushing scalar and gaugino masses up.Comment: 16 pages, 7 figures. v2 has bigger figures and fixed typos. v3 has
clarified explanation of our handling of signal systematic
General analysis of signals with two leptons and missing energy at the Large Hadron Collider
A signal of two leptons and missing energy is challenging to analyze at the
Large Hadron Collider (LHC) since it offers only few kinematical handles. This
signature generally arises from pair production of heavy charged particles
which each decay into a lepton and a weakly interacting stable particle. Here
this class of processes is analyzed with minimal model assumptions by
considering all possible combinations of spin 0, 1/2 or 1, and of weak
iso-singlets, -doublets or -triplets for the new particles. Adding to existing
work on mass and spin measurements, two new variables for spin determination
and an asymmetry for the determination of the couplings of the new particles
are introduced. It is shown that these observables allow one to independently
determine the spin and the couplings of the new particles, except for a few
cases that turn out to be indistinguishable at the LHC. These findings are
corroborated by results of an alternative analysis strategy based on an
automated likelihood test.Comment: 18 pages, 3 figures, LaTe
Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1
Although the ability of bioactive lipid sphingosine-1-phosphate (S1P) to positively regulate anti-apoptotic/pro-survival responses by binding to S1P1 is well known, the molecular mechanisms remain unclear. Here we demonstrate that expression of S1P1 renders CCL39 lung fibroblasts resistant to apoptosis following growth factor withdrawal. Resistance to apoptosis was associated with attenuated accumulation of pro-apoptotic BH3-only protein Bim. However, although blockade of extracellular signal-regulated kinase (ERK) activation could reverse S1P1-mediated suppression of Bim accumulation, inhibition of caspase-3 cleavage was unaffected. Instead S1P1-mediated inhibition of caspase-3 cleavage was reversed by inhibition of phosphatidylinositol-3-kinase (PI3K) and protein kinase C (PKC), which had no effect on S1P1 regulation of Bim. However, S1P1 suppression of caspase-3 was associated with increased expression of anti-apoptotic protein Mcl-1, the expression of which was also reduced by inhibition of PI3K and PKC. A role for the induction of Mcl-1 in regulating endogenous S1P receptor-dependent pro-survival responses in human umbilical vein endothelial cells was confirmed using S1P receptor agonist FTY720-phosphate (FTY720P). FTY720P induced a transient accumulation of Mcl-1 that was associated with a delayed onset of caspase-3 cleavage following growth factor withdrawal, whereas Mcl-1 knockdown was sufficient to enhance caspase-3 cleavage even in the presence of FTY720P. Consistent with a pro-survival role of S1P1 in disease, analysis of tissue microarrays from ER+ breast cancer patients revealed a significant correlation between S1P1 expression and tumour cell survival. In these tumours, S1P1 expression and cancer cell survival were correlated with increased activation of ERK, but not the PI3K/PKB pathway. In summary, pro-survival/anti-apoptotic signalling from S1P1 is intimately linked to its ability to promote the accumulation of pro-survival protein Mcl-1 and downregulation of pro-apoptotic BH3-only protein Bim via distinct signalling pathways. However, the functional importance of each pathway is dependent on the specific cellular context
Collider signatures of goldstini in gauge mediation
We investigate the collider signatures of the multiple goldstini scenario in
the framework of gauge mediation. This class of models is characterized by a
visible sector (e.g. the MSSM or any extension) coupled by gauge interactions
to more than one SUSY breaking sector. The spectrum consists of a light
gravitino LSP, behaving as a goldstino, and a number of neutral fermions (the
pseudo-goldstini) with a mass between that of the LSP and that of the lightest
particle of the observable sector (LOSP). We consider the two situations where
the LOSP is either a gaugino-like neutralino or a stau and we assume only one
pseudo-goldstino of a mass of O(100) GeV. The coupling of the LOSP to the
pseudo-goldstino can be enhanced with respect to those of the gravitino giving
rise to characteristic signatures. We show that the decay modes of the LOSP
into a SM particle and a pseudo-goldstino can be significant. For both LOSP
scenarios we analyze (pseudo)-goldstini production at colliders. Compared to
standard gauge mediation the final state spectrum is softer and more
structured.Comment: v2: analysis of the stau LOSP scenario added, sections rearranged,
and Introduction and Conclusions rewritten to include the added scenario.
Version to appear in JHE
Spin and Chirality Effects in Antler-Topology Processes at High Energy Colliders
We perform a model-independent investigation of spin and chirality
correlation effects in the antler-topology processes
at high energy colliders with polarized
beams. Generally the production process
can occur not only through the -channel exchange of vector bosons,
, including the neutral Standard Model (SM) gauge bosons,
and , but also through the - and -channel exchanges of new
neutral states, and , and the -channel
exchange of new doubly-charged states, . The general set of
(non-chiral) three-point couplings of the new particles and leptons allowed in
a renormalizable quantum field theory is considered. The general spin and
chirality analysis is based on the threshold behavior of the excitation curves
for pair production in collisions with
longitudinal and transverse polarized beams, the angular distributions in the
production process and also the production-decay angular correlations. In the
first step, we present the observables in the helicity formalism. Subsequently,
we show how a set of observables can be designed for determining the spins and
chiral structures of the new particles without any model assumptions. Finally,
taking into account a typical set of approximately chiral invariant scenarios,
we demonstrate how the spin and chirality effects can be probed experimentally
at a high energy collider.Comment: 50 pages, 14 figures, 6 tables, matches version published in EPJ
Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis
Ca2+ transfer from endoplasmic reticulum (ER) to mitochondria can trigger apoptotic pathways by inducing release of mitochondrial pro-apoptotic factors. Three different types of inositol 1,4,5-trisphosphate receptor (IP3R) serve to discharge Ca2+ from ER, but possess some peculiarities, especially in apoptosis induction. The anti-apoptotic protein Akt can phosphorylate all IP3R isoforms and protect cells from apoptosis, reducing ER Ca2+ release. However, it has not been elucidated which IP3R subtypes mediate these effects. Here, we show that Akt activation in COS7 cells, which lack of IP3R I, strongly suppresses IP3-mediated Ca2+ release and apoptosis. Conversely, in SH-SY 5Y cells, which are type III-deficient, Akt is unable to modulate ER Ca2+ flux, losing its anti-apoptotic activity. In SH-SY 5Y-expressing subtype III, Akt recovers its protective function on cell death, by reduction of Ca2+ release. Moreover, regulating Ca2+ flux to mitochondria, Akt maintains the mitochondrial integrity and delays the trigger of apoptosis, in a type III-dependent mechanism. These results demonstrate a specific activity of Akt on IP3R III, leading to diminished Ca2+ transfer to mitochondria and protection from apoptosis, suggesting an additional level of cell death regulation mediated by Akt
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